N-tert-Butoxycarbonyl-L-lysine methyl ester hydrochloride
Boc-Lys-OMe.HCl
CAS: 55757-60-3
Molecular Formula: C12H24N2O4
N-tert-Butoxycarbonyl-L-lysine methyl ester hydrochloride - Names and Identifiers
| Name | Boc-Lys-OMe.HCl |
| Synonyms | boc-lys-omeCl BOC-LYS-OM.HCL Boc-Lys-OMe.HCl BOC-LYS-OME HCL Boc-Lys(Ac)-Oh Hcl BOC-LYS(AC)-OH HCL (S)-Boc-lysinemethylester BOC-L-LYSINE METHYL ESTER HYDROCHLORIDE methyl N~2~-(tert-butoxycarbonyl)lysinate N-tert-Butoxycarbonyl-L-lysine methyl ester hydrochloride N2-[(1,1-DIMETHYLETHOXY)CARBONYL]-L-LYSINE METHYL ESTER HCL |
| CAS | 55757-60-3 |
| InChI | InChI=1/C12H24N2O4/c1-12(2,3)18-11(16)14-9(10(15)17-4)7-5-6-8-13/h9H,5-8,13H2,1-4H3,(H,14,16) |
N-tert-Butoxycarbonyl-L-lysine methyl ester hydrochloride - Physico-chemical Properties
| Molecular Formula | C12H24N2O4 |
| Molar Mass | 260.33 |
| Density | 1.056±0.06 g/cm3(Predicted) |
| Boling Point | 374.7±37.0 °C(Predicted) |
| Flash Point | 180.424°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 11.16±0.46(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.466 |
N-tert-Butoxycarbonyl-L-lysine methyl ester hydrochloride - Introduction
Boc-Lys-OMe.HCl(Boc-Lys-OMe · HCl) is an organic compound. Its nature is as follows:
1. Appearance: Boc-Lys-OMe · HCl is white crystal or crystalline powder.
2. melting point: about 135-145 ℃.
3. Solubility: Boc-Lys-OMe · HCl has low solubility in water and is insoluble in general organic solvents such as ethers and alcohols.
Boc-Lys-OMe · HCl is commonly used in biochemical research and drug synthesis and has the following uses:
1. Protein synthesis: Boc-Lys-OMe · HCl can be used as a protecting group of Lys (lysine) to protect the Lys functional group during the synthesis of polypeptides or proteins.
2. Drug research: Boc-Lys-OMe · HCl can be used for the synthesis of anti-tumor drugs, antiviral drugs and antibacterial drugs.
3. Chemical synthesis: Boc-Lys-OMe · HCl can be used as a starting material or intermediate in organic synthesis.
The preparation method of Boc-Lys-OMe · HCl can generally be synthesized by the following steps:
1. Lys is reacted with tert-butyryl chloride (Boc-Cl) by an appropriate method to generate Boc-Lys.
2. react Boc-Lys with methyl formate to generate Boc-Lys-OMe.
3. Finally, the Boc-Lys-OMe is reacted with hydrochloric acid to generate Boc-Lys-OMe · HCl.
When using and storing Boc-Lys-OMe · HCl, the following safety information needs to be observed:
1. Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, safety glasses and protective masks when using.
2. Maintain a well-ventilated laboratory environment during operation.
3. Try to avoid inhalation or intake of compounds, avoid direct contact.
4. storage should be sealed in a cool, dry place, away from the fire and oxidant.
1. Appearance: Boc-Lys-OMe · HCl is white crystal or crystalline powder.
2. melting point: about 135-145 ℃.
3. Solubility: Boc-Lys-OMe · HCl has low solubility in water and is insoluble in general organic solvents such as ethers and alcohols.
Boc-Lys-OMe · HCl is commonly used in biochemical research and drug synthesis and has the following uses:
1. Protein synthesis: Boc-Lys-OMe · HCl can be used as a protecting group of Lys (lysine) to protect the Lys functional group during the synthesis of polypeptides or proteins.
2. Drug research: Boc-Lys-OMe · HCl can be used for the synthesis of anti-tumor drugs, antiviral drugs and antibacterial drugs.
3. Chemical synthesis: Boc-Lys-OMe · HCl can be used as a starting material or intermediate in organic synthesis.
The preparation method of Boc-Lys-OMe · HCl can generally be synthesized by the following steps:
1. Lys is reacted with tert-butyryl chloride (Boc-Cl) by an appropriate method to generate Boc-Lys.
2. react Boc-Lys with methyl formate to generate Boc-Lys-OMe.
3. Finally, the Boc-Lys-OMe is reacted with hydrochloric acid to generate Boc-Lys-OMe · HCl.
When using and storing Boc-Lys-OMe · HCl, the following safety information needs to be observed:
1. Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, safety glasses and protective masks when using.
2. Maintain a well-ventilated laboratory environment during operation.
3. Try to avoid inhalation or intake of compounds, avoid direct contact.
4. storage should be sealed in a cool, dry place, away from the fire and oxidant.
Last Update：2024-04-09 21:00:56
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